- 1. Mast cells in the dermis was increased in SSc patients.
- 2. The number of dermis mast cells were associated with the severity of
- skin sclerosis.
- 3. Mast cells in pulmonary interstitium was increased co-localizing with the pulmonary artery in a SSc patient complicated with PAH.
- 4. Mast cells in skin and lung of SSc patient produce TGF-b and PDGF.
The involvement of mast cells in the formation of scleroderma